Deprescribing in a geriatric virtual ward

Overview

Initiative type

Model of Care

Status

Deliver

Published

June 2025

Summary

Medication deprescribing by a geriatric virtual ward was achievable in community-dwelling older adults, offering a novel and favourable setting to reduce medication-related harm.

Dates: November 2024 - June 2025

Implementation sites: Logan Hospital

This project was presented as a poster at CEQ Showcase 2026 (PDF 1.8MB).

Aim

To explore Geriatric Evaluation and Management in the Home service deprescribing practices and identify opportunities for quality improvement through analysis of deprescribing trends, post-discharge outcomes and consumer feedback.

Outcomes

  • Two thirds (68%, n=53/78) of patients had medications deprescribed by the service between November 2024- March 2025
  • A total of 157 medicines were deprescribed, most commonly supplements (26%), medications contributing to Drug Burden Index (25%) and antihypertensives (10%)
  • A reduction in Dug Burden Index was observed (n= 39, p=0.048)
  • Most (79%, n=42/53) patients with deprescribed medicines completed a post-discharge telephone survey
  • 87% (n=112/129) of medicines remained deprescribed (mean follow-up 109 days)
  • Participants reported overall high satisfaction and felt well supported during the deprescribing process
  • Key barriers to maintenance of deprescribed medicines were limited patient access to general practitioners post-discharge (n=3) and unsuccessful weaning of antidepressants (n=3/9)

Background

Deprescribing 'the planned and supervised reduction or cessation of medications that may no longer be beneficial or may cause harm - is increasingly recognised as central to quality use of medicines in older adults, however, translating deprescribing into routine clinical practice remains challenging (1).

Barriers include clinician concerns about withdrawal effects or symptom recurrence, patient reluctance to discontinue long-standing therapies, and system-level issues such as time constraints, fragmented care, and unclear responsibility across transitions of care (1-2).

Medication-related harm in older adults is driven not only by medication count but also by cumulative exposure to medicines with anticholinergic or sedative properties. The Drug Burden Index is a validated measure of this exposure and is associated with impaired physical and cognitive function, increased falls, hospitalisation, and mortality (3).

Reducing Drug Burden Index is therefore an important and clinically meaningful target for deprescribing interventions, particularly among older adults with complex medication regimens.

Integrated, multidisciplinary models of care may help address common barriers to deprescribing. Geriatric Evaluation and Management in the Home is an emerging model within Australian health services that delivers sub-acute, hospital-level care in the patient's home as a hospital substitution or avoidance pathway. Care is led by a geriatrician and delivered by a multidisciplinary team, with medication review and deprescribing embedded as routine components of care. The Geriatric Evaluation and Management in the Home model provides a time-limited, controlled environment that enables close monitoring of medication changes, iterative dose adjustment, and coordinated communication with general practitioners and specialists, facilitating implementation of deprescribing recommendations in the home setting and reducing the risk of unintended medication re-initiation after discharge.

Despite these theoretical advantages, deprescribing within Geriatric Evaluation and Management in the Home models have not been systematically evaluated. Existing literature focuses largely on inpatient, residential aged care, or primary care settings, with limited evidence from home-based hospital-substitution models (4-5).

This study addressed this gap by exploring deprescribing practices within an Australian Geriatric Evaluation and Management in the Home service. The findings will inform future service development, strengthen medication optimisation initiatives, and support continuity of care after discharge.

Methods

This was a single-centre ambispective cohort study for patients 65 years or older discharged from the Logan Geriatric Evaluation and Management in the Home service between November 2024 and March 2025. Deprescribing activity was obtained retrospectively from electronic hospital records. Deprescribing was defined as medication cessation, dose reduction, or initiation of a tapering plan without substitution for the same indication.

Patients with one or more medications deprescribed during admission were recruited for a prospective follow-up telephone survey. Discharge medication records were compared to the patient's medication regimen three-months post-discharge to determine if deprescribing was maintained. Descriptive statistics and paired t-tests were used to analyse the data. Inductive thematic analysis was used to evaluate consumer feedback and identify opportunities for quality improvement.

Discussion

Geriatric Evaluation and Management in the Home-led deprescribing was frequently implemented and largely maintained, supporting the feasibility of deprescribing within a structured, virtual ward model of care. By exploring local deprescribing practices, we gained valuable insight into Geriatric Evaluation and Management in the Home service delivery and, importantly, into consumer experience. High levels of patient and carer satisfaction provided reassurance that deprescribing approaches were acceptable, supportive, and aligned with consumer priorities.

A key learning from this work was highlighting the importance of planning beyond the point at which deprescribing recommendations are made. The findings have been applied locally to ensure Geriatric Evaluation and Management in the Home clinicians consider what occurs after discharge, including access to general practitioners, clarity of primary care handover, and the need for timely geriatrician follow-up for more complex or high-risk medication changes. Clear, consumer-friendly communication emerged as central to maintained deprescribing, supporting patient understanding and confidence during transitions of care.

Several limitations were acknowledged. This was a single-centre study with a modest sample size, and findings may not be generalisable, particularly given the clinician-dependent nature of deprescribing in current practice. Formal clinical outcomes and quality of life measures were not assessed, however, satisfaction responses suggest that deprescribing did not result in perceived harm or deterioration and that patients were able to remain safely at home. The study also did not capture missed opportunities for deprescribing or instances in which patients declined deprescribing recommendations, which may underestimate the complexity of deprescribing decision-making.

This project achieved important quality improvement outcomes. It will increase awareness of the Logan Geriatric Evaluation and Management in the Home service, demonstrate that deprescribing of high-risk medications can be implemented and maintained beyond discharge, and highlight system enablers required to support continuity of medication optimisation. Importantly, it serves as an accountability mechanism to ensure that deprescribing practices reflect what matters most to patients and their carers. These findings support ongoing refinement of deprescribing processes within Geriatric Evaluation and Management in the Home services and inform future service development across similar virtual ward models, within and beyond Queensland Health.

References

  1. Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing. JAMA Intern Med. 2015;175(5):827-834. doi:10.1001/jamainternmed.2015.0324
  2. Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544. Published 2014 Dec 8. doi:10.1136/bmjopen-2014-006544
  3. Hilmer SN, Mager DE, Simonsick EM, et al. A drug burden index to define the functional burden of medications in older people. Arch Intern Med. 2007;167(8):781-787. doi:10.1001/archinte.167.8.781
  4. Omuya H, Nickel C, Wilson P, Chewning B. A systematic review of randomised-controlled trials on deprescribing outcomes in older adults with polypharmacy. Int J Pharm Pract. 2023;31(4):349-368. doi:10.1093/ijpp/riad025
  5. Chua S, Todd A, Reeve E, et al. Deprescribing interventions in older adults: An overview of systematic reviews. PLoS One. 2024;19(6):e0305215. Published 2024 Jun 17. doi:10.1371/journal.pone.0305215

Key contact

Tiina Brown

Pharmacist

Logan Hospital

Metro South Hospital and Health Service

Email:  Tiina.Brown@health.qld.gov.au